Weekly COVID-19 cases (April 4December 25, 2021) and associated deaths (April 4December 4, 2021) by vaccination status, including additional and booster doses starting October 3, were reported from 25 state and local health departments that routinely link case surveillance to vaccination data from immunization registries; 2- and 5-week reporting lag times for cases and deaths, respectively, allowed for more complete reporting, data linkage, and mortality ascertainment. 81 percent of reported hospitalizations with COVID-19 as the primary diagnosis/cause of admission were in unvaccinated or not fully vaccinated people. A graph, with annotations added by Insider, showing US hospitalization . Among these, encounters discharged from the ED, fully vaccinated but not . Excluded were partially vaccinated persons who had received at least one FDAauthorized or approved vaccine dose but did not complete a primary series 14 days before collection of a specimen with SARS-CoV-2 RNA or antigen detected. Each CI represents the remaining variation in observed weekly incidence rates and resulting incidence rate ratios. *** https://www.cdc.gov/nchs/data/statnt/statnt24.pdf. Proportion of Adults in the COVID-19Associated Hospitalization Surveillance Network (COVID-NET) Catchment Area and, Figure 2.. During the early rollout of vaccines, vaccinated people represented a small share of total deaths, but experts warned that the share would likely rise simply because vaccinated people were representing a growing share of the population. Vaccine Breakthrough Unit, Surveillance and Analytics Team. Clipboard, Search History, and several other advanced features are temporarily unavailable. Thank you for taking the time to confirm your preferences. CDC COVID-19 Response Team. Among all COVID deaths in the weeks leading up through Aug. 30, just 97 were fully vaccinated people who contracted breakthrough cases of the coronavirus. This chart displays the 7-day trend in overall and Covid-19-specific hospitalization occupancy data to help understand changes in capacity and level of stress on hospitals, including: Beds occupied by Covid-19 patients (ICU and Inpatient), which appear in orange. To interpret IRR changes, age-standardized crude vaccine effectiveness (VE) was estimated as (1 [incidence in vaccinated / incidence in unvaccinated]). All HTML versions of MMWR articles are generated from final proofs through an automated process. Three-Week Moving Average Population-Based Rates a of COVID-19Associated Hospitalizations Among Unvaccinated and Vaccinated, MeSH Analysis periods were categorized as April 4May 29, 2021 (pre-Delta: 0.1%7% proportion range), May 30July 3, 2021 (Delta emergence: 14%69%), July 4November 27, 2021 (Delta predominance: 81%99%), and November 28December 25, 2021, (Omicron emergence: 1%72%). New hospitalizations with laboratory-confirmed COVID-19 among fully vaccinated and unvaccinated adults, vaccine coverage, and estimated vaccine effectiveness, by age New York, May 3-July 25 . ** 95% CIs were calculated after detrending underlying linear changes in weekly incidence rates using piecewise linear regression. The CDC monitors rates of COVID-19 cases and deaths and laboratory-confirmed COVID-19 hospitalizations by vaccination status and age group, and publishes data and interactive tables on its website monthly, where anyone can download them. During AugustNovember 2021, CDC recommended additional primary COVID-19 vaccine doses among immunocompromised persons and booster doses among persons aged 18 years (5). There are several factors at play here, including a rising share of the population that is vaccinated, waning immune protection and low uptake of boosters, and changes in immunity among the unvaccinated. * Events per 100,000 population. COVID-19 is on track to be the third leading cause of death in 2022, for the third year in a row, and this year, about half of those deaths over the course of the year were among people who had at least their primary series. Similarly, as the share of the population with a booster rose somewhat during 2022, the share of deaths among boosted people also rose. CDC is not responsible for the content Department of Health and Human Services. Third, national variant prevalence estimates were used, but prevalence differed by jurisdiction over time. CDC. But by January 2022, as we showed in an . However, the rising share of the population that is vaccinated is only part of the story and does not seem to explain all of the rise in the share of deaths that are among vaccinated people over the last year. Townhall weekly columnist. Of the 623 breakthrough deaths among vaccinated people in the state, 89% of them were people 65 years old and older. of pages found at these sites. -. Cookies used to make website functionality more relevant to you. In all jurisdictions, local health authorities review data to determine whether the death was associated with COVID-19 (through a review of vital records, cause of death, and/or other public health investigations or data sources), though methods vary by state or jurisdiction. Washington Offices and Barbara Jordan Conference Center: 1330 G Street, NW, Washington, DC 20005 | Phone 202-347-5270, www.kff.org | Email Alerts: kff.org/email | facebook.com/KaiserFamilyFoundation | twitter.com/kff. On October 21, 2021, CDC recommended a booster dose for adults aged 18 years who had received the Janssen vaccine and for Pfizer-BioNTech or Moderna primary series vaccine recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings (https://www.cdc.gov/media/releases/2021/p1021-covid-booster.html). If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. A spokesperson for the CDC, Kristen Nordlund, told the New York Times the agency has been slow to release some data because its not ready for prime time and because of the fear that it could be misinterpreted. Over the study period, age-adjusted VE against COVID-related hospitalization was relatively steady, from 91.9% to 95.3%. 5.8% were fully vaccinated plus a booster shot. For primary mRNA vaccination series, the vaccine product of the second dose was used to determine primary series product type. Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. Murphy, Murphy: No link between wind power and NJ whale deaths, Surprise visit to Ukraine NJ Gov. The data for COVID-19-associated hospitalizations by vaccination status from January 2021 to Feb. 26 were posted on March 24, and then updated on March 31. Sect.241(d); 5 U.S.C.0 Sect.552a; 44 U.S.C. From January to April 2022, when the Omicron variant was predominant, hospitalization rates were 10.5 times higher in unvaccinated persons and 2.5 times higher in vaccinated persons with no booster dose, respectively, compared with those who had received a booster dose. On the show, Kheriaty, who is against COVID-19 vaccine mandates and was recently fired from the University of California, Irvine for refusing to get vaccinated, questioned the effectiveness of vaccines that have proved to be effective in trials and in the real world. adds wastewater data to its Covid-19 tracker. Jennifer Kates Follow @jenkatesdc on Twitter Breakthrough infection and hospitalization data vs. the unvaccinated on a rolling basis per 100K New York residents Ultimately, there's no sugarcoating any component of the numbers right now . endorsement of these organizations or their programs by CDC or the U.S. The new data, published in the U.S . Data reduction and error analysis for the physical sciences. All of the authorized and approved vaccines are effective at preventing severe COVID-19. Saving Lives, Protecting People, Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants, https://ndc.services.cdc.gov/case-definitions/coronavirus-disease-2019-2021/, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines.html, https://www.cdc.gov/media/releases/2021/s0813-additional-mRNA-mrna-dose.html, https://www.cdc.gov/media/releases/2021/p0924-booster-recommendations-.html, https://www.cdc.gov/media/releases/2021/p1021-covid-booster.html, https://www.cdc.gov/media/releases/2021/s1119-booster-shots.html, https://www.cdc.gov/media/releases/2021/s1129-booster-recommendations.html, https://cdn.ymaws.com/www.cste.org/resource/resmgr/pdfs/pdfs2/20211222_interim-guidance.pdf, https://covid.cdc.gov/covid-data-tracker/#variant-proportions, https://www.census.gov/programs-surveys/popest/data/tables.2019.html, https://www.cdc.gov/nchs/data/statnt/statnt20.pdf, https://www.medrxiv.org/content/10.1101/2022.01.07.22268919v1.full, https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4011905, https://covid.cdc.gov/covid-data-tracker/#rates-by-vaccine-status, https://covid.cdc.gov/covid-data-tracker/#covidnet-hospitalizations-vaccination, https://doi.org/10.1146/annurev-ecolsys-112414-054242, https://www.cdc.gov/nchs/data/statnt/statnt24.pdf, Centers for Disease Control and Prevention, U.S. Department of Health & Human Services, Omicron emergence (first week in December 2021). Conclusions: Through this preliminary data, we can conclude that patient can develop severe and critical COVID-19 infection despite being vaccinated but this proportion . Amelia G. Johnson, DrPH1,*; Avnika B. Amin, PhD1,*; Akilah R. Ali, MPH1; Brooke Hoots, PhD1; Betsy L. Cadwell, PhD1; Shivani Arora, MPH2; Tigran Avoundjian, PhD3; Abiola O. Awofeso, DVM4; Jason Barnes, MBA5; Nagla S. Bayoumi, DrPH6; Katherine Busen, MPH7; Carolyn Chang, MPH8; Mike Cima, PhD9; Molly Crockett, MPH10; Alicia Cronquist, MPH11; Sherri Davidson, PhD12; Elizabeth Davis, MA13; Janelle Delgadillo5; Vajeera Dorabawila, PhD14; Cherie Drenzek, DVM15; Leah Eisenstein, MPH16; Hannah E. Fast, MPH17; Ashley Gent, MPH16; Julie Hand, MSPH18; Dina Hoefer, PhD14; Corinne Holtzman, MPH19; Amanda Jara, DVM15; Amanda Jones, MPH20; Ishrat Kamal-Ahmed, PhD21; Sarah Kangas, MPH22; FNU Kanishka, MPH21; Ramandeep Kaur, PhD12; Saadiah Khan, MPH6; Justice King, MSc1; Samantha Kirkendall, MS23; Anna Klioueva, MPH24; Anna Kocharian, MS22; Frances Y. Kwon, MPH2; Jacqueline Logan, MPH25; B. Casey Lyons, MPH26; Shelby Lyons, MPH18; Andrea May, MPH27; Donald McCormick; MSHI9; Erica Mendoza, MAS24; Lauren Milroy, MPH28; Allison ODonnell, MPH10; Melissa Pike, MPH11; Sargis Pogosjans, MPH3; Amy Saupe, MPH19; Jessica Sell, MPH8; Elizabeth Smith, MPH15; Daniel M. Sosin, MD13; Emma Stanislawski, MPH13; Molly K. Steele, PhD1; Meagan Stephenson, MPH1; Allen Stout, MS7; Kyle Strand21; Buddhi P. Tilakaratne, PhD4; Kathryn Turner, PhD23; Hailey Vest, MPH28; Sydni Warner, MS22; Caleb Wiedeman, MPH25; Allison Zaldivar, MPH27; Benjamin J. Still, hospitalizations are up 90 percent since July 4, and more than 300 people are now hospitalized in New York City with Covid-19. In order to be counted as vaccinated, a person must be at least two weeks out from completing their primary series before testing positive (for example, at least 14 days after completing two doses of the mRNA vaccine). However, this protection from a past infection can also diminish over time, which is why it is still recommended that unvaccinated people with prior COVID-19 infections get vaccinated and stay up-to-date on boosters. This analysis represents the combined impact of BNT162b2 (Pfizer-BioNTech), mRNA-1273 (Moderna), and Ad.26.COV2.S (Janssen [Johnson & Johnson]) COVID-19 vaccines, which had different clinical efficacies against confirmed infection; fully vaccinated persons also include those persons who received additional primary doses and booster doses starting in mid-August. To subscribe via email notifications, you must first sign in. Accessed 1 Apr 2022. This change requires a reload. The https:// ensures that you are connecting to the For . The largest hospitals have seen the highest number of COVID cases among their staff, but not necessarily bypercentage of their workforce. The number of observations informing each CI reflects the number of weeks per period: AprilMay (7), June (5), JulyNovember (21), and December (4). The Advisory Committee on Immunization Practices interim recommendations for additional primary and booster doses of COVID-19 vaccinesUnited States, 2021. The number of observations informing each CI reflects the number of weeks per period: OctoberNovember (7), and December (4). Alabama, Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Idaho, Indiana, Kansas, Louisiana, Massachusetts, Michigan, Minnesota, Nebraska, New Jersey, New Mexico, New York, New York City (New York), Rhode Island, Seattle/King County (Washington), Tennessee, Texas, Utah, and Wisconsin. Protection against infection and death during the Delta-predominant period and against infection during Omicron emergence were higher among booster vaccine dose recipients, especially among persons aged 5064 and 65 years. Although the data we use in this analysis are not broken out by time since last vaccination, given the plateauing vaccination rate, it is likely that many of the vaccinated people who died of COVID-19 had the primary series or a booster many months or even over a year earlier, meaning they were less protected against severe illness than they once were. Claudia Corwin, MD, MPH, an occupational medicine specialist and associate director of the University Employee Health Clinic, breaks down the biggest differences between delta variant COVID-19 infection in vaccinated and unvaccinated people. analysis posted on the Peterson-KFF Health System Tracker, unvaccinated people are at much greater risk of death, 14% of adults overall and 31% of older adults (65 years and older) have received the latest bivalent boosters. A large majority of new hospitalizations and deaths from COVID-19 are occurring among unvaccinated people. Paz-Bailey G, Sternberg M, Kugeler K, et al. The waning protection from vaccines is why CDC recommends recent booster shots, and why its especially important for people at higher risk to stay up-to-date on boosters. COVID-19 as an Occupational Disease-Temporal Trends in the Number and Severity of Claims in Germany. In January, the average daily rate for an adult being hospitalized with COVID was about 4.45 per 100,000 people. Analysis periods were determined based on variant proportion estimates in the United States. Age-specific vaccine administration data were used for incidence rate denominators; numbers of unvaccinated persons were estimated by subtracting the numbers of fully and partially vaccinated persons from 2019 U.S. intercensal population estimates. A continuity correction assumed at 5% of each age group and jurisdiction would always be unvaccinated (i.e., fully vaccinated coverage 95%). The surge in Covid-19 cases fueled by the Delta variant and vaccine hesitancy has now led to increasing rates of hospitalizations and deaths. During the most recent coronavirus update on Monday, Gov. The SARS-CoV-2 B.1.1.529 (Omicron) variant emerged in the United States during December 2021 (6) and by December 25 accounted for 72% of sequenced lineages (7). Eligible persons should stay up to date with COVID-19 vaccinations. 95% CIs were calculated after detrending underlying linear changes in weekly incidence rates using piecewise linear regression. In fall 2021, about 3 in 10 adults dying of COVID-19 were vaccinated or boosted. All information these cookies collect is aggregated and therefore anonymous. IRRs during the pre-Delta period and period of Delta predominance periods were relatively stable, followed by declines corresponding to transitions in variant prevalence (Supplementary Figure, https://stacks.cdc.gov/view/cdc/113543). Age-standardized case IRRs among unvaccinated persons compared with fully vaccinated persons with a booster dose declined from 13.9 during OctoberNovember to 4.9 during December, representing potential decreases in crude VE for infection from 93% to 80%, respectively. Filling the need for trusted information on national health issues, Cynthia Cox Follow @cynthiaccox on Twitter A COVID-19 case in a fully vaccinated person with a booster dose occurred when a person had SARS-CoV-2 RNA or antigen detected on a respiratory specimen collected 14 days after receipt of at least one additional or booster dose of any COVID-19 vaccine on or after August 13, 2021. Standardized definitions were used for COVID-19 cases in fully vaccinated or unvaccinated persons, COVID-19 cases in fully vaccinated persons with booster doses, and COVID-19associated deaths,** with specimen collection dates used as time points. New variants combined with a reduction in masking and other non-pharmaceutical interventions may also lead to more transmission, which can in turn lead to more deaths. Summary. However, only 14% of adults overall and 31% of older adults (65 years and older) have received the latest bivalent boosters. Average weekly incidence rates and rate ratios are provided by age group, primary series vaccine type, and overall; overall and vaccine-specific rates were standardized by age, according to the enumerated 2000 U.S. Census age distribution. Before From other data, we know there continue to be more overall deaths than there were before the pandemic (excess deaths). A COVID-19 case in an unvaccinated person occurred when the person did not receive any FDAauthorized COVID-19 vaccine doses before the specimen collection date. Fewer than 0.5% of COVID-19 deaths across all ages in 2022 have been among people under 25. Ann Clin Lab Sci. -, Bajema KL, Dahl RM, Prill MM, et al. While COVID-19 cases continue to spike across the US, the overwhelming majority of deaths and hospitalizations from the virus continue to overwhelmingly be among unvaccinated Americans, according . On August 13, 2021, CDC recommended an additional Pfizer-BioNTech or Moderna primary series dose for persons with moderately or severely immunocompromise. With the Omicron variant, combined with a reduction in other preventive measures like masking, vaccinated people may be more likely to be infected than they were this time last year. TheNovavax vaccine, which was authorized in July 2022, had a 90.4% efficacy in preventing symptomatic COVID-19 in adults, prior to the emergence of the omicron variant. Alabama, Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Idaho, Indiana, Kansas, Louisiana, Massachusetts, Michigan, Minnesota, Nebraska, New Jersey, New Mexico, New York, New York City (New York), Rhode Island, Seattle/King County (Washington), Tennessee, Texas, Utah, and Wisconsin. A COVID-19 case in a fully vaccinated person with a booster dose occurred when a person had SARS-CoV-2 RNA or antigen detected on a respiratory specimen collected 14 days after receipt of at least 1 additional or booster dose of any COVID-19 vaccine on or after August 13, 2021 (this definition does not distinguish between vaccine recipients who are immunocompromised and are receiving an additional dose versus those who are not immunocompromised and receiving a booster dose). Vaccine effectiveness of primary series and booster doses against Omicron variant COVID-19associated hospitalization in the United States. CDC now recommends the updated bivalent booster shot for everyone ages 5 year and above. COVID cases rising in NJ are due to the spread of the delta variant among unvaccinated residents, said Gov. During April 4December 25, 2021, a total of 6,812,040 COVID-19 cases among unvaccinated persons and 2,866,517 cases among fully vaccinated persons were reported among persons aged 18 years in 25 U.S. jurisdictions; 94,640 and 22,567 COVID-19associated deaths among unvaccinated and fully vaccinated persons, respectively, were reported by December 4 (Table 1). Cases have increased 14% in the last two weeks, city data shows. The vaccines are not perfect, and the vast majority of vulnerable people have been vaccinated, so the small proportion who get seriously ill still amount to a lot of people. What are the implications for public health practice? For deaths, a single week (November 28December 4, 2021) of data was reported during the December 2021 period of Omicron emergence, but the proportion of Omicron variant during that first week was approximately 1%. The New York Times story cited by Kheriaty added that although the agency had been collecting wastewater data showing SARS-CoV-2 RNA levels from some states and localities since the beginning of the pandemic information that could have been useful to detect new surges of cases the data were only made public on Feb. 4. Average weekly incidences were calculated by age group (1849, 5064, and 65 years), vaccination status, and primary series vaccine product (Ad.26.COV2.S [Janssen {Johnson & Johnson}], BNT162b2 [Pfizer-BioNTech], and mRNA-1273 [Moderna]) during each period; rates overall and by vaccine product were age-standardized using the 2000 U.S. Census standard population. IRRs were calculated by dividing incidence among unvaccinated persons by incidence among fully vaccinated persons (overall and by receipt of booster doses); after detrending the underlying linear changes in incidence, 95% CIs were calculated based on the remaining variation in observed weekly rates (8,9). There is simply no other way to interpret this data, the vaccines work and they work well., Dr. Ed Lifshitz, the director of communicable disease services for the New Jersey Health Department, said with the most recent data those who are not vaccinated are 7 times as likely to be hospitalized if they get ill.. Weekly rates of COVID-19 hospitalizations and deaths by vaccination status are published monthly by the Centers for Disease Control and Prevention on its website. MMWR Morb Mortal Wkly Rep 2021;70:17314. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. by vaccination status and age group, and publishes data and interactive tables on its website monthly, where anyone can download them. Murphy said 99.99% of the 32,000 COVID-19 hospitalizations between Jan. 19 and July 12 were unvaccinated individuals. But a viral tweet claimed the CDC is no longer releasing the information. Rates of COVID-19 deaths by vaccination status are reported based on when the patient was tested for COVID-19, not the date they died. Booster shots arerecommendedfor most people, as theseincrease and prolongprotection against severe disease and also provide some temporary protection against infection and milder illness. IRRs and VE were higher among persons who were fully vaccinated and had received a booster dose than among fully vaccinated persons who had not received a booster dose for cases and deaths during the period of Delta predominance and for cases during the period of Omicron emergence in December. FOIA 33.6% were "under-vaccinated," meaning they either received only one shot of the Pfizer or Moderna vaccine, or have not received a booster shot. Other lineages prior to the Delta transition included Alpha (>50%), Gamma, Epsilon, Iota, Mu, and other lineages. and are much worse at preventing infection or mild disease. . Conflict of Interest Disclosures: Drs Yousey-Hindes, Lynfield, Sutton, Talbot, and Meek reported grants from US Centers for Disease Control and Prevention (CDC) during the conduct of the study. Rates of laboratory-confirmed COVID-19 hospitalizations by vaccination status. Fully vaccinated COVID-19 hospital patients had an aOR of 0.33 for death or the need for invasive mechanical ventilation. In an email sent to FactCheck.org on March 28, Morefield said he decided to remove his tweet after admitting that the CDC does release some -though not all or enough- data on an agency website. The goal of the project is to increase exposure to accurate information about COVID-19 and vaccines, while decreasing the impact of misinformation. Cases were excluded in partially vaccinated persons who received at least one FDA-authorized or approved vaccine dose but did not complete a primary series 14 days before collection of a respiratory specimen with SARS-CoV-2 RNA or antigen detected. Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. Why are these basic metrics being withheld from the American people? Kheriaty, published on Feb. 20 that reported the CDC had withheld critical data on boosters, hospitalizations and wastewater analyses. Vaccinations for COVID-19 began being administered in the U.S. on Dec. 14, 2020. When the Omicron variant emerged during December 2021, case IRRs decreased to 4.9 for fully vaccinated persons with booster doses and 2.8 for those without booster doses, relative to OctoberNovember 2021. Atlanta, GA: US Department of Health and Human Services, CDC; 2021. Disclaimer. Abbreviations: FDA = Food and Drug Administration; IRR=incidence rate ratio; NC=not calculated for the single reported week of deaths in December 2021. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Key Points. Phil Murphy said hewants to increase the capacity at some hospitals by 50to 100 beds indoorsor in tents on their campus,and not in a field station like one established at the Meadowlands convention center in 2020. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). She has askedfor a FEMA strike force to be deployed at depleted hospitals and the National Guard to fill in at nursing homes where almost 6,000 staffers have recently tested positive. To subscribe to the Rates of COVID-19 Cases or Deaths by Age Group and Vaccination Status dataset via an RSS reader, use one of the following links: Download as RSS COVID-19-associated hospitalizations among vaccinated and unvaccinated adults 18 years - COVID-NET, 13 states, January 1 - July 24, 2021. medRxiv.org.
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